* |
If the form is filed by more than one reporting person, see Instruction 5(b)(v). |
** |
Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) |
The shares are held as follows: 242,925 shares by MPM BioVentures III, L.P. (???BV III???), 3,612,947 shares by MPM BioVentures III-QP, L.P. (???BV III QP???), 109,115 shares by MPM BioVentures III Parallel Fund, L.P. (???BV III PF???), 305,339 shares by MPM BioVentures GmbH & Co. Beteiligungs KG (???BV III KG???) and 69,952 shares by MPM Asset Management Investors 2003 BV III, LLC (???BV AM LLC???). MPM BioVentures III GP, L.P (???BV III GP???) and MPM BioVentures III LLC (???BV III LLC???) are the direct and indirect general partners of BV III, BV III QP, BV III PF and BV III KG and the Reporting Person is a member of BV III LLC. The Reporting Person is a member of BV AM LLC. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. |
(2) |
The shares are held as follows: 48,585 shares by BV III, 722,589 shares by BV III QP, 21,823 shares by BV III PF, 61,068 shares by BV III KG and 13,990 shares by BV AM LLC. BV III GP and BV III LLC are the direct and indirect general partners of BV III, BV III QP, BV III PF and BV III KG and the Reporting Person is a member of BV III LLC. The Reporting Person is a member of BV AM LLC. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. |