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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940 |
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Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. | |||
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. | SEC 1474 (9-02) |
1. Title of Derivative Security (Instr. 3) |
2. Conversion or Exercise Price of Derivative Security | 3. Transaction Date (Month/Day/Year) | 3A. Deemed Execution Date, if any (Month/Day/Year) | 4. Transaction Code (Instr. 8) |
5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5) |
6. Date Exercisable and Expiration Date (Month/Day/Year) |
7. Title and Amount of Underlying Securities (Instr. 3 and 4) |
8. Price of Derivative Security (Instr. 5) |
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) |
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) |
11. Nature of Indirect Beneficial Ownership (Instr. 4) |
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Code | V | (A) | (D) | Date Exercisable | Expiration Date | Title | Amount or Number of Shares |
Reporting Owner Name / Address | Relationships | |||
Director | 10% Owner | Officer | Other | |
MPM BIOEQUITIES MASTER FUND LP C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVENUE, 31ST FLOOR BOSTON, MA 02199 |
X | |||
MPM BIOEQUITIES GP LP C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVENUE, 31ST FLOOR BOSTON, MA 02199 |
X | |||
MPM BIOEQUITIES GP LLC C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVENUE, 31ST FLOOR BOSTON, MA 02199 |
X | |||
MPM BIOEQUITIES FUND GMBH & CO KG C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVENUE, 31ST FLOOR BOSTON, MA 02199 |
X | |||
EVNIN LUKE C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVENUE, 31ST FLOOR BOSTON, MA 02199 |
X | |||
GADICKE ANSBERT C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVENUE, 31ST FLOOR BOSTON, MA 02199 |
X | |||
LIPTAK ROBERT C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVENUE, 31ST FLOOR BOSTON, MA 02199 |
X | |||
EMSTER KURT VON C/O MPM ASSET MANAGEMENT 111 HUNTINGTON AVENUE, 31ST FLOOR BOSTON, MA 02199 |
X |
By Luke Evnin manager of MPM BioEquities GP LLC, the general partner of MPM BIoEquities GP, LP, the general partner of MPM BioEquities Master Fund, L.P. /s/ Luke Evnin | 02/23/2004 | |
**Signature of Reporting Person | Date | |
By Luke Evnin manager of MPM BioEquities GP LLC, the general partner of MPM BIoEquities GP, LP /s/ Luke Evnin | 02/23/2004 | |
**Signature of Reporting Person | Date | |
By Luke Evnin manager of MPM Bioequities GP LLC /s/ Luke Evnin | 02/23/2004 | |
**Signature of Reporting Person | Date | |
By Luke Evnin manager of MPM BioEquities GP LLC, the general partner of MPM BIoEquities GP, LP, the general partner of MPM BioEquities Fund GmbH & Co. KG /s/ Luke Evnin | 02/23/2004 | |
**Signature of Reporting Person | Date | |
/s/ Luke Evnin | 02/23/2004 | |
**Signature of Reporting Person | Date | |
/s/ Ansbert Gadicke | 02/23/2004 | |
**Signature of Reporting Person | Date | |
/s/ Robert Liptak | 02/23/2004 | |
**Signature of Reporting Person | Date | |
/s/ Kurt von Emster | 02/23/2004 | |
**Signature of Reporting Person | Date |
* | If the form is filed by more than one reporting person, see Instruction 4(b)(v). |
** | Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) | See Form 4 filed for MPM BioVentures III-QP, L.P. for additional members of this joint filing. The shares were sold as follows: 9,648 by MPM BioVentures III, L.P. ("BVIII"); 143,488 by MPM BioVentures III-QP, L.P. ("BVIII QP"); 12,126 by MPM BioVentures III GmbH & Co. Beteiligungs KG ("BVIII KG"); 4,333 by MPM Bioventures III Parallel Fund, L.P. ("BVIII PF"); and 2,778 by MPM Asset Management Investors 2003 BVIII LLC ("BVAM LLC"). MPM BioVentures III GP, L.P. ("BVIII GP") and MPM BioVentures III LLC ("BVIII LLC") are the direct and indirect partners of BVIII, BVIII QP, BVIII PF and BVIII KG. |
(2) | The shares are held as follows: 182,511 by MPM BioEquities Master Fund, L.P. ("BEMF") and 100 by MPM BioEquities Fund GmbH & Co. KG ("BEFG"), who are under common control with BVIII; 233,277 by BVIII; 3,469,459 by BVIII QP; 293,213 by BVIII KG; 104,782 by BVIII PF; and 67,174 by BVAM LLC. MPM BioEquities GP, LP ("BE LP") and MPM BioEquities GP, LLC ("BE LLC"), are the direct and indirect general partners of BEMF and BEFG. Luke Evnin ("LE"), Ansbert Gadicke ("AG"), Nicholas Galakatos ("NG"), Dennis Henner ("DH"), Michael Steinmetz ("MS") and Kurt Wheeler ("KW") are the members of BVIII LLC. LE, AG, Robert Liptak and Kurt von Emster are members of BE LLC. LE, AG, NG, DH, Nicholas Simon, III, MS and KW are members of BVAM LLC. Each member of the group disclaims beneficial ownership of the securities except to the extent of its pecuniary interest therein. |