Rigel has an exclusive, worldwide license agreement with Forma Therapeutics (now Novo Nordisk) for olutasidenib in all indications. In December 2022, the U.S. FDA approved REZLIDHIA (olutasidenib).
Rigel in-licensed exclusive, worldwide rights to develop, manufacture, and commercialize olutasidenib, an oral, mutant isocitrate dehydrogenase-1 (mIDH1) inhibitor, in all indications, including relapsed/refractory acute myeloid leukemia and other malignancies.
Under the terms of the agreement, Forma (now Novo Nordisk) received an upfront payment and is eligible to receive additional regulatory, approval, and commercial sales milestones, and receives tiered royalties on net sales.
Rigel is responsible for the commercialization of olutasidenib in the U.S., and intends to work with partners to further develop and commercialize olutasidenib outside the U.S.