Annual report pursuant to Section 13 and 15(d)

INCOME TAXES (Tables)

v3.19.3.a.u2
INCOME TAXES (Tables)
12 Months Ended
Dec. 31, 2019
INCOME TAXES  
Schedule of components of the entity's deferred tax assets

Significant components of our deferred tax assets are as follows (in thousands):

 

 

 

 

 

 

 

 

 

 

 

December 31,

 

 

    

2019

    

2018

 

Deferred tax assets

 

 

 

 

 

 

 

Net operating loss carryforwards

 

$

240,157

 

$

226,388

 

Orphan drug and research and development credits

 

 

59,603

 

 

55,276

 

Deferred compensation

 

 

8,817

 

 

7,155

 

Lease liabilities

 

 

6,989

 

 

 —

 

Capitalized research and development expenses

 

 

2,282

 

 

424

 

Other, net

 

 

529

 

 

809

 

Deferred tax liabilities

 

 

 

 

 

 

 

Operating lease right-of-use asset

 

 

(6,719)

 

 

 —

 

Total net deferred tax assets

 

 

311,658

 

 

290,052

 

Less: valuation allowance

 

 

(311,658)

 

 

(290,052)

 

Deferred tax assets, net of allowance

 

$

 —

 

$

 —

 

 

Schedule of reconciliation of the statutory federal income tax rate to the effective tax rate

 

 

 

 

 

 

 

 

 

 

Year Ended December 31,

 

 

    

2019

    

2018

    

2017

 

Federal statutory tax rate

 

(21.0)

%  

(21.0)

%  

(34.0)

%

Federal statutory rate reduction

 

 —

%  

 —

%  

160.2

%

State, Net of Federal Benefit

 

0.1

%  

 —

%  

 —

%

Valuation allowance

 

21.7

%  

16.3

%  

(126.5)

%

Stock compensation

 

2.8

%  

8.2

%  

5.7

%

Orphan drug and research and development credits

 

(5.1)

%  

(3.7)

%  

(3.6)

%

Other, net

 

1.5

%  

0.2

%  

(1.8)

%  

Effective tax rate

 

0.0

%  

0.0

%  

0.0

%  

 

Schedule of activity related to the entity's gross unrecognized tax benefits

The following table summarizes the activity related to our gross unrecognized tax benefits (in thousands):

 

 

 

 

 

 

 

 

 

 

 

Year Ended December 31,

 

 

    

2019

    

2018

 

Balance at the beginning of the year

 

$

7,849

 

$

7,430

 

Increase related to current year tax positions

 

 

509

 

 

419

 

Balance at the end of the year

 

$

8,358

 

$

7,849