Quarterly report pursuant to Section 13 or 15(d)

SPONSORED RESEARCH AND LICENSE AGREEMENTS AND GOVERNMENT CONTRACT (Details)

v3.22.2
SPONSORED RESEARCH AND LICENSE AGREEMENTS AND GOVERNMENT CONTRACT (Details)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 18 Months Ended
Apr. 30, 2021
USD ($)
Feb. 28, 2021
USD ($)
Jan. 31, 2021
USD ($)
Feb. 29, 2020
USD ($)
Dec. 31, 2019
Oct. 31, 2019
USD ($)
agreement
Jan. 31, 2019
USD ($)
Oct. 31, 2018
USD ($)
Jun. 30, 2022
USD ($)
Mar. 31, 2022
USD ($)
Jun. 30, 2021
USD ($)
Mar. 31, 2021
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2021
USD ($)
Dec. 31, 2020
Jun. 30, 2022
USD ($)
Dec. 31, 2021
USD ($)
Collaborations                                  
Upfront payment received                         $ 125,000        
Accretion expense                 $ 0   $ 1,000   700 $ 1,100      
Payment of cost share to collaboration partner                         8,346        
Accounts receivable                 17,198       17,198     $ 17,198 $ 15,472
License agreement with unrelated third party                                  
Collaborations                                  
Revenue recognized                           4,000      
Proceeds from License Fees Received   $ 4,000                              
One-time fee received from license rights granted   $ 4,000                              
Specified Development Events [Member]                                  
Collaborations                                  
Contingent payments                         279,500        
Specified Regulatory Events [Member]                                  
Collaborations                                  
Contingent payments                         283,100        
Specified Product Launch Events [Member]                                  
Collaborations                                  
Contingent payments                         796,000        
Development and regulatory milestones by non-CNS disease products                                  
Collaborations                                  
Contingent payments                         330,000        
Development and regulatory milestones by non-CNS disease products | Milestone payments on a product-by-product basis                                  
Collaborations                                  
Contingent payments                         100,000        
Development and regulatory milestones by CNS disease products                                  
Collaborations                                  
Contingent payments                         255,000        
Development and regulatory milestones by CNS disease products | Milestone payments on a product-by-product basis                                  
Collaborations                                  
Contingent payments                         150,000        
Maximum                                  
Collaborations                                  
Contingent payments                         1,300,000        
Grifols                                  
Collaborations                                  
Contingent payments                         277,500        
Upfront payment received             $ 30,000                    
Revenue, remaining performance obligation                                 5,000
Deferred revenue                 200       200     200 700
Revenue, cumulative catch-up                   $ 25,000              
Grifols | Commercial milestones                                  
Collaborations                                  
Contingent payments             $ 297,500                    
Grifols | Upon EMA approval of fostamatinib for treatment of chronic ITP                                  
Collaborations                                  
Revenue, cumulative catch-up                   $ 20,000              
Kissei                                  
Collaborations                                  
Contingent payments               $ 147,000                  
Upfront payment received               $ 33,000                  
Revenue, remaining performance obligation                 33,000       33,000     33,000  
Knight | Commercial and license agreements                                  
Collaborations                                  
Upfront payment received                 2,000                
Knight | Maximum | Commercial milestones | Commercial and license agreements                                  
Collaborations                                  
Contingent payments                 20,000                
fostamatinib                                  
Collaborations                                  
Revenue recognized                 0   5,500   0 8,500   10,500  
Government contract     $ 16,500                            
Remaining amount of government award expected to be received in succeeding periods                         6,000        
fostamatinib | Grifols                                  
Collaborations                                  
Revenue recognized                 1,200   0   1,200 1,000      
Collaborative payment received       $ 20,000                          
Markup percentage         30.00%                        
fostamatinib | Grifols | Upon EMA approval of fostamatinib for treatment of chronic ITP                                  
Collaborations                                  
Contingent payments       17,500                          
fostamatinib | Grifols | Creditable advance royalty payment                                  
Collaborations                                  
Collaborative payment received       $ 2,500                          
fostamatinib | Grifols | Maximum                                  
Collaborations                                  
Royalty payment as a percentage of net sales                             30.00%    
fostamatinib | Kissei                                  
Collaborations                                  
Revenue recognized                 2,500   0   2,600 0      
Deferred revenue                 1,400       1,400     1,400 1,400
Collaborative payment received $ 5,000                                
fostamatinib | Medison Pharma | Financing arrangement                                  
Collaborations                                  
Upfront payment received           $ 5,000                      
Financing liability with accreted interest expense                 5,700       5,700     5,700 5,600
Accretion expense                 0   300   0 300      
Deferred revenue                 100       $ 100     100  
fostamatinib | Medison Pharma | Commercial and license agreements                                  
Collaborations                                  
Upfront payment received           $ 5,000                      
Number of agreements | agreement           2                      
R552                                  
Collaborations                                  
Company's percentage of development costs                         20.00%        
Financing component liability                 57,900       $ 57,900     57,900  
Financing liability interest accretion discount rate                         6.40%        
Financing liability with accreted interest expense                 53,000       $ 53,000     53,000 $ 60,700
Development costs due to collaboration partner                 8,300       8,300     8,300  
Revenue, remaining performance obligation                 67,100       67,100     67,100  
R552 | Maximum                                  
Collaborations                                  
Funding commitment                 65,000       65,000     $ 65,000  
Non-CNS penetrant IP                                  
Collaborations                                  
Revenue recognized                       $ 60,400          
CNS penetrant IP                                  
Collaborations                                  
Revenue recognized                 300   3,300   500 3,500      
CNS penetrant IP | Licensed Rights                                  
Collaborations                                  
Revenue, remaining performance obligation                     6,700     6,700      
Research and development services | Grifols                                  
Collaborations                                  
Revenue recognized                 $ 200   $ 400   $ 500 $ 400