Quarterly report pursuant to Section 13 or 15(d)

CONDENSED STATEMENTS OF CASH FLOWS

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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Operating activities    
Net loss $ (17,464) $ (18,193)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:    
Depreciation and amortization 324 435
Stock-based compensation expense 1,438 2,054
Changes in assets and liabilities:    
Accounts receivable 8 5,644
Prepaid and other current assets 766 367
Other assets 46 28
Accounts payable (339) (477)
Accrued compensation (3,099) 882
Accrued research and development 2,286 455
Other accrued liabilities (286) 458
Deferred revenue (4,834) 27,928
Deferred rent and other long term liabilities (1,266) (1,594)
Net cash provided by (used in) operating activities (22,420) 17,987
Investing activities    
Purchases of short-term investments (47,446) (49,977)
Maturities of short-term investments 40,996 59,520
Capital expenditures (321) (32)
Net cash provided by (used in) investing activities (6,771) 9,511
Financing activities    
Net proceeds from issuances of common stock upon exercise of options and participation in Purchase Plan 4 17
Net cash provided by financing activities 4 17
Net increase (decrease) in cash and cash equivalents (29,187) 27,515
Cash and cash equivalents at beginning of period 43,456 15,203
Cash and cash equivalents at end of period $ 14,269 $ 42,718