Quarterly report pursuant to Section 13 or 15(d)

Sponsored Research and License Agreements (Details)

v3.19.2
Sponsored Research and License Agreements (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Jan. 31, 2019
Oct. 31, 2018
Jun. 30, 2019
Dec. 31, 2018
Jun. 30, 2019
Kissei          
Collaborations          
Upfront payment received   $ 33,000,000      
Contingent payments   $ 147,000,000      
Revenue recognized       $ 30,600,000  
Grifols          
Collaborations          
Upfront payment received $ 30,000,000       $ 5,000,000
Deferred revenue related to upfront payment     $ 25,400,000   25,400,000
Grifols | Research Services          
Collaborations          
Revenue recognized     73,000   144,000
Grifols | Commercial Milestones          
Collaborations          
Contingent payments 297,500,000        
fostamatinib | Kissei          
Collaborations          
Deferred revenue related to upfront payment     2,300,000   2,300,000
Revenue recognized     $ 77,000   $ 105,000
fostamatinib | Grifols | Prior written notice following the second anniversary of the first MAA approval of fostamatinib in Europe and Turkey          
Collaborations          
Right to terminate agreement within number of months after second anniversary         6 months
fostamatinib | Grifols | Terminated agreement upon prior written notice within six months after second anniversary of agreement          
Collaborations          
Contingent upfront fee, refund requirement 25,000,000        
fostamatinib | Grifols | EMA approval of fostamatinib for treatment of chronic ITP          
Collaborations          
Contingent payments $ 20,000,000        
fostamatinib | Grifols | Maximum          
Collaborations          
Royalty payment as a percentage of net sales 30.00%